Apple ITunes Helper – ITUNESHELPER.EXE
ITunesHelper.exe installs with the iTunes Player for Windows and Mac users. iTunes lets you download music from the iTunes music store, to create libraries and play lists, to burn CDs, and transfer music to your iPod player. iTunes can also be used as an aggregator (or podcatcher) to subscribe to podcasts. More information can be found at http://www.apple.com/itunes/download/.
If run on system startup, iTunesHelper recognizes when your iPod player is plugged in. It then starts the iTunes program. Some claim that running it on system startup makes iTunes launch faster as well. If you don't use an iPod or if you don't mind starting the software manually, you might consider disabling this file in your Startup Programs using WinPatrol. Disabling it should keep it from bothering you. If you remote it, it may be replaced the next time you launch the iTunes software. You'll find iTunes support at http://www.apple.com/support/itunes/.